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DeCS
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Descriptor English:
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Receptor, PAR-2
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Descriptor Spanish:
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Receptor PAR-2
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Descriptor Portuguese:
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Receptor PAR-2
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Synonyms English:
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PAR 2 Receptor
PAR-2 Receptor
PAR2 Receptor
Protease Activated Receptor 2
Protease-Activated Receptor 2
Proteinase Activated Receptor 2
Receptor 2, Protease-Activated
Receptor, PAR 2
Receptor, PAR2
Receptor, Trypsin
Receptors, Trypsin
Trypsin Receptor
Trypsin Receptors
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Tree Number:
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D12.776.543.750.695.035
D12.776.543.750.792.249
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Definition English:
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A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence. |
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History Note English:
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2004; use RECEPTOR, PAR-2 (NM) 1994-2003; for TRYPSIN RECEPTOR use RECEPTOR, PAR-2 (NM) 1986-2003
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Allowable Qualifiers English:
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Record Number:
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38263
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Unique Identifier:
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D044464
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Occurrence in VHL:
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Similar:
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DeCS
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